Search results for "Intravitreal ranibizumab"

showing 5 items of 5 documents

Intravitreal ranibizumab treatment of retinal angiomatous proliferation

2010

. Purpose:  To determine the efficacy of intravitreal injections of ranibizumab in the treatment of retinal angiomatous proliferation (RAP) in neovascular age-related macular degeneration. Methods:  Retrospective, consecutive case series of 26 eyes (26 patients) treated with intravitreal injections of 0.5 mg ranibizumab for RAP. Patients received intravitreal injections at monthly intervals during upload phase for a 3-month period. Results:  Mean visual acuity before treatment was 0.75 ± 0.38logMAR (mean ± SD, n = 26). In the upload phase, mean visual acuity improved 4 weeks after the initial injection to 0.6 ± 0.37logMAR (n = 26) and to 0.53 ± 0.34logMAR (n = 26) 4 weeks after the third mo…

MaleAngiomatosismedicine.medical_specialtyVisual acuitygenetic structuresVisual AcuityAngiogenesis InhibitorsFoveal thicknessRetinal NeovascularizationAntibodies Monoclonal Humanizedchemistry.chemical_compoundOpticsRanibizumabOphthalmologymedicineHumansMaintenance phaseAgedRetrospective StudiesAged 80 and overbusiness.industryRetinalGeneral MedicineMiddle AgedMacular degenerationmedicine.diseaseeye diseasesOphthalmologyTreatment OutcomechemistryIntravitreal InjectionsRetreatmentWet Macular DegenerationFemalesense organsRanibizumabIntravitreal ranibizumabmedicine.symptombusinessTomography Optical Coherencemedicine.drugActa Ophthalmologica
researchProduct

Angioid streak-related choroidal neovascularization treated by intravitreal ranibizumab.

2010

PURPOSE The purpose of this study was to report the visual outcome of intravitreal therapy with ranibizumab of choroidal neovascularization secondary to angioid streaks after 1-year follow-up. METHODS Nine patients (age, 58 +/- 4 years; range, 53-65 years) were treated with off-label intravitreal injections of 0.3 mg ranibizumab. Primary outcomes were best-corrected visual acuity changes (Early Treatment Diabetic Retinopathy Study logarithm of the minimum angle of resolution and letters) and optical coherence tomography macular thickness changes. RESULTS Mean follow-up was 14 months (+/-2; range, 12-18 months). Mean visual acuity was 0.52 logarithm of the minimum angle of resolution and 30 …

MaleVascular Endothelial Growth Factor Amedicine.medical_specialtyVisual acuitygenetic structuresVisual AcuitymonoclonalAngiogenesis InhibitorsAntibodies Monoclonal HumanizedLoading doseChoroidal neovascularization; male; treatment outcome; injections; middle aged; vascular endothelial growth factor a; female; vitreous body; humans; retreatment; visual acuity; angiogenesis inhibitors; aged; angioid streaks; antibodies monoclonalInjectionsNeovascularizationOptical coherence tomographyOphthalmologyRanibizumabMedicineantibodiesHumansANTI-VEGFAgedintravitreal ranibizumabmedicine.diagnostic_testbusiness.industrySettore MED/30 - Malattie Apparato VisivoAntibodies MonoclonalGeneral MedicineDiabetic retinopathyMiddle Agedmedicine.diseaseeye diseasesChoroidal NeovascularizationVitreous BodyOphthalmologyAngioid streaksChoroidal neovascularizationTreatment OutcomeRetreatmentAngioid StreaksFemalemedicine.symptomRanibizumabbusinessAngioid streak-related choroidal neovascularizationmedicine.drugRetina (Philadelphia, Pa.)
researchProduct

Rapid Regression of Exudative Maculopathy in Idiopathic Retinitis, Vasculitis, Aneurysms and Neuroretinitis Syndrome after Intravitreal Ranibizumab

2012

The idiopathic retinitis, vasculitis, aneurysms and neuroretinitis syndrome is a rare retinal vascular disorder characterized by multiple leaking aneurysmal dilations, retinal vasculitis, neuroretinitis and peripheral vascular ischemia. Visual loss mainly occurs due to the development of retinal neovascularization and/or exudative maculopathy. Although the treatment of choice has not yet been established, retinal photocoagulation seems to be the best option to control the disease and to prevent its progression. Herein, we report a case of idiopathic retinitis, vasculitis, aneurysms and neuroretinitis syndrome with both retinal neovascularization and macular exudation successfully managed wi…

medicine.medical_specialtyExudative maculopathyRapid regressiongenetic structuresbusiness.industryRetinal vasculitisPublished online: August 2012medicine.diseaseeye diseasesOphthalmologylcsh:Ophthalmologylcsh:RE1-994OphthalmologyRanibizumabmedicineIdiopathic retinitisIdiopathic retinitis vasculitis aneurysms and neuroretinitis syndromeRetinal Vascular DisorderRanibizumabIntravitreal ranibizumabbusinessVasculitisExudative maculopathymedicine.drugCase Reports in Ophthalmology
researchProduct

Intravitreal ranibizumab for symptomatic drusenoid pigment epithelial detachment without choroidal neovascularization in age-related macular degenera…

2011

Roberto Gallego-Pinazo,1,2 Ana Marina Suelves-Cogollos1, Ester Francés-Muñoz,1 J María Millán,2,3 J Fernando Arevalo,4 J Luis Mullor,5 Manuel Díaz-Llopis,1,2,61Department of Ophthalmology, Hospital Universitario La Fe, Valencia, Spain; 2Centro de Investigación Biomédica en Red de Enfermedades Raras, Valencia, Spain; 3Department of Genetics, Hospital Universitario La Fe, Valencia, Spain; 4Retina and Vitreous Service, Clínica Oftalmológica Centro Caracas, Caracas, Venezuela; 5Unit of Experimental Ophthalmology, Fundación para la Investigación del Hospital Universitario La F…

medicine.medical_specialtyVisual acuitygenetic structureschoroidal neovascularizationOptical coherence tomographyOphthalmologymedicineMetamorphopsiadrusenoid pigment epithelial detachmentranibizumabage-related macular degenerationOriginal Researchsoft drusenmedicine.diagnostic_testbusiness.industryClinical OphthalmologyDiabetic retinopathyMacular degenerationmedicine.diseaseeye diseasesOphthalmologyChoroidal neovascularizationsense organsRanibizumabmedicine.symptomIntravitreal ranibizumabbusinessmedicine.drugClinical Ophthalmology
researchProduct

Prophylaxis of Macular Edema with Intravitreal Ranibizumab in Patients with Diabetic Retinopathy after Cataract Surgery: A Pilot Study

2011

The purpose of this study was to evaluate the effectiveness of intravitreal ranibizumab (Lucentis, Genentech, South San Francisco, Calif, USA) combined with cataract surgery for the prevention of clinically significant macular edema (CSME) in patients with diabetic retinopathy (DR). This prospective interventional case series included fifty-four eyes of 54 patients with a previous diagnosis of nonproliferative diabetic retinopathy (NPDR) without macular edema preoperatively. Subjects were assigned in a 1 : 1 ratio to receive an intraoperative intravitreal ranibizumab injection (n=27) or not (control group,n=27) associated with standardised phacoemulsification surgery. The main outcome measu…

medicine.medical_specialtygenetic structuresArticle Subjectbusiness.industrymedicine.medical_treatmentIncidence (epidemiology)After cataractPhacoemulsificationDiabetic retinopathyCataract surgerymedicine.diseaseeye diseasesSurgeryOphthalmologylcsh:Ophthalmologylcsh:RE1-994OphthalmologymedicineClinical StudyIn patientIntravitreal ranibizumabbusinessMacular edemaJournal of Ophthalmology
researchProduct